CBD OIL FOR NAUSEA

The anti-emetic (effective against nausea and vomiting) properties of cannabis are probably one of the most recognized and studied medicinal application of the plant, and a clear body of evidence supports its efficacy. The research demonstrates that manipulation of the endocannabinoid system regulates nausea and vomiting in humans and other animals, whether the condition is related to toxins, hormones, or motion. Cannabis has been used to treat nausea and vomiting across cultures for millennia, and in the mid-1970s scientific research began to focus on the treatment of these symptoms among chemotherapy patients.

The first studies used high-THC cannabis successfully and resulted in the development of a synthetic THC pharmaceutical called Marinol, still prescribed today for nausea and appetite stimulation related to cancer and AIDS. However, evidence shows that Marinol and other synthetic versions of cannabinoids are not as effective as plant-based products for many diseases. For nausea and vomiting in particular, inhaled products have proven to have a higher success rate since they bypass the GI system and have immediate effect, but oral cannabinoids can also work for chronic issues.

By 2002, researchers began to turn toward cannabinoids without psychoactive side effects, namely CBD, for their therapeutic value in the treatment of nausea. Unlike THC, CBD has a low affinity for the CB1 and CB2 receptors but appears to work indirectly on the 5-HT receptor, in the serotonin family of neurotransmitters.