SAFE CBD DOSING FOR PETS

We know cannabis is a complex combination of various forms of THC, CBD, terpenes, and flavonoids. It is, however, impractical to calculate the concentration of all of the compounds present in a given plant as a means of determining dosage. Since THC and CBD are the most biologically active cannabinoids, medical cannabis dosing is based on these two components.

When determining the dosing of cannabis for pets, the primary necessity is accurate labeling. Without this information, carefully calculated doses mean nothing. Assuming the product being used is labeled accurately, the other consideration to take into account is the biphasic dosing curve.

BIPHASIC DOSING CURVE

Cannabis displays a phenomenon called a biphasic dosing curve; in short, it refers to the optimal dose for a given condition and individual. Dosing below or above this optimum can result in a decreased effect of the medication. There is effectively a “sweet spot” with cannabis where it works optimally.

Given that there is no way to know exactly what the ideal dose is for any individual, the best strategy is to begin with a low dose and slowly increase on a weekly basis until the optimal response is found. Decreased efficacy from exceeding the optimal dose is different from overdosing in the sense of toxicity.

When purchasing a product specifically designed for pets, determining a dose should be easy: simply follow the directions on the label. But, even with CBD, and as stated previously, it is still advisable to start at the low end of the dosing range provided and slowly increase over time. This will prevent excessive sedation, which can occur even with CBD products. Cannabis products produced for human consumption may have dosing information on them, but, once again, dogs and cats are not “small humans.” Dosing them as such may result in a trip to the emergency room.

The following dosage guidelines for dogs and cats have been derived from a combination of research data and veterinary experience. Recommendations vary by individual and condition, so always consult an experienced veterinarian prior to giving cannabis to your pet.

Dose: 0.1–0.5 mg/kg/day
Calculated dose should be divided for twice-daily dosing
Doses up to 5 mg/kg/day have been reported for difficult seizure cases
Start low and slowly increase to adjust for the biphasic dosing curve